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  • Suspension culture Systems
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Cell Culture

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CELSTIR - Suspension culture Systems

Wheaton Science Products has long been an innovator in cell culture flasks. The Wheaton Magna FlexR impeller produces high-yield cultures by maintaining even circulation while keeping cultures in suspension. Slow acceleration and slow stop from the Wheaton Micro-StirR stirrer prevent cell detachment from microcarriers.
Wheaton also invented an adjustable impeller flask that does not have a rod extending through the top of a flask. CelstirR flasks feature adjustable blade impeller for increased aeration and dimpled bottom to prevent the accumulation of cells under the impeller.

Micro carrier systems

Designed for use with microcarrier cultures Side arms for 500 mL - 6 L flasks allow vented caps which enables the flask to “breath” while protecting from contamination Gentle, even stirring action The Wheaton Magna Flex Spinner Flasks feature a flex-type, bulb-shaped glass impeller that rotates from a fixed position above liquid level around an indentation in the base of the flask. Primarily designed for use with microcarrier cultures, this unique stirring system increases stirring efficiency and provides a gentle, even circulation throughout the flask while keeping the beads in suspension. All flasks have been proportioned to provide a head space ratio of 1:1 or greater. A removable stainless steel pin immobilizes the impeller during handling or decanting to prevent damage to cells or microcarriers. Sizes 500 mL and larger.

Fermentors

No data available

Bio reactors

The Cell Optimizer System is a complete, small volume cell culture bioreactor. The system provides a quick and accurate determination of optimum environmental cell growth parameters. Key areas of use are:
www.wheatonsci.com

Key areas of use are:
Small culture bioreactor Cell culture process optimization Insect cell culture techniques Hybridoma cell culture methods $Viral infection studies The Cell Optimizer SystemR is a complete, small-volume cell culture bioreactor. This system provides a quick and accurate determination of optimum environmental cell growth parameters. Cell growth in the Cell Optimizer System takes place in a 250 mL, 500 mL, 1 liter or 3 liter working volume spinner flask with four (4) sidearms.
The system includes a Control Tower™, Control Tower Support Unit and Micro-StirR magnetic stirrer. The Control Tower and support unit automatically controls pH via base addition and CO2 gas, and dissolved oxygen utilizing air, O2 and N2 gases. Temperature is maintained by the use of a heating pad that eliminates the need for an incubator. Stirring speed (5-200 RPM) is achieved by manually setting the Micro-StirR magnetic stirrer. Foam and nutrient feed control are available as options. The support unit includes a combination heater/pump module for temperature control and liquid base addition. A four-gas mixing module provides controlled additions of necessary gases to the vessel head space (and/or optional sparger). One year warranty.

Mini Pilot Plant
Key areas of use are:
Large volume cell culture bioreactor Scale cultures up to production volume Antibody or virus production Pilot plant studies Economical mass cell production Production of proteins or other cell products

Roller systems

Wheaton R2P system.
The Wheaton Modular Cell Production Roller Culture Apparatus allows flexibility for scale-up and production of monolayer cell cultures in standard roller bottles. It accepts bottles from 108 to 121 mm in diameter and up to 550 mm in length. The system consists of a base drive unit and five-position roller deck to which additional roller decks can be added. A powerful DC motor, with soft-start speed control, drives the bottles through a series of durable nonslip belts. The all-position drive model is a positive traction drive system for lightweight plastic bottles in which each roller is individually driven. Also included is a locking speed control knob that prevents accidental change in rotation rates.

Bench top roller culture system.

This conventional-type roller culture rack is designed to roll vessels 108 to 121 mm in diameter and up to 290 mm long. The two outside rollers can be movedinward to accommodate bottles as small as 75 mm in diameter. Each deck can accommodate two vessels.

Mini Bottle Bench Top Roller culture System.

Allows precise rotation speed Small scale mixing and agitation Small footprint Conforms to UL, CSA, and CE Standards 1 year warranty
Perfect for Wheaton 30 mL or larger serum bottles, 100-125 mL media bottles or 38 x 200 mm culture tubes for the growth and observation of various cell cultures such as, single chicken or rat embryos. The Wheaton Mini Bottle Roller Culture Apparatus accommodates bottles 38 to 60 mm in diameter, up to 240 mm long, with bottle speeds of 3 to 45 RPM (38 mm bottle) and 2 to 30 RPM (60 mm bottle).

Stirrers

Biostir & Microstir Magnetic stirrers.
Regular stirrers to Hotplates with rgular tops and seramic tops, MRC offers one of the best range of magnetic stirrers.
Computerized stirrer control Rotation speed clearly visible for consistent results Variety of operating modes for suspension or microcarrier cultures Constant Speed Mode - Soft start to a constant stirring speed, this mode is used for suspension cultures. Interval Start Mode - This mode turns the stirrer on and off using the soft start and stop for a set number of cycles, after which the stirrer runs at a constant speed that may differ from the speed used to attach the cells. This mode is useful for attaching cells to micro-carrier beads. There is no need to watch the culture and turn on the stirrer for a constant stir mode after the cells have attached.
2-Speed Stirring Mode - The stirrer slowly starts to a set speed, which is held for a user-defined period. The stirrer then softly changes to a final constant speed. This mode is also useful for microcarrier applications. 2 year warranty Conforms to UL, CSA, and CE Standards Optional remote control.

Cell density measurement

No Data Available

High throughput cell lysing system

No Data Available